What's Needle Cartridge? The needle cartridge uses 12 micro-sized 33 gauge micro-needles to stimulate the dermis faster than a manual dermal roller, resulting in shorter treatment times. With an adjustable needle (depth/length), the Derma pen needles vertically pierce the skin to enhance rejuvenation results, maintain epidermal integrity and reduce patient down time. The penetration depth of the needles can be adjusted directly on the device, so there is no need to change the tip in order to treat areas that require deeper or more superficial treatments. The area of the tip which comes in direct contact with the skin is about 1 centimeter in diameter, which makes it easy to treat hard to reach areas inaccessible to dermal rollers. You can adjust the length of needles and the vibrating frequency, according to your need (0.25mm, 0.5mm, 1.0mm, 1.5mm, and 2.0mm) Nano Needle Nano-needles do not puncture the skin, but ensure better integration of the active ingredients and blood circulation of the skin. These are not real-sense needles, but very thin pyramid-shaped plastic tips that do not hurt the skin. The application is therefore completely painless and can also be carried out every day if necessary. Particularly suitable for better ingest active substances/sera on the face, neck and décolleté. A forcation of collagen production - as for the "good" Microneedling tips (i.e. with stainless steel needles that puncture the skin) - is therefore not or very weak. Great care tool. Nano pins for motorized Derma Pen Rejuvenation: firming the skin, reducing wrinkles and fine lines. Meso-Glow: management of vitamins and other anti-aging agents Acne Scar Reduction: Reduces permanent scars and acne scars. Reduction of stretch brand. Stimulation of hair growth (premature baldness). Brightening (melasma). Firms the skin. Advantages of collagen induction therapy. Minimum risks Economical. Short healing time No permanent skin damage No increased sensitivity to the sun. Made under topical anesthesia. all skin types can be treated. treat thin or laser skin. The body produces natural collagen for lasting results. Better penetration of applied products.