FRIO wallets keep insulin safe for up to 45 hours (lasts up to 5 times longer than an ice pack). Although activated by water, a feature of the product is that after towel-drying, the FRÍO wallet is dry to the touch. The Cambrelle Pouch (DuPont Product) increases the wallet's efficiency and allows it to be carried safely in your pocket or a bag as required. Each item is re-usable and can be used either continuously or intermittently.